N M Dean Selected Research

ISIS 22023

8/2000

Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis.

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N M Dean Research Topics

Disease

4	Neoplasms (Cancer) 07/2001 - 03/2000
4	Glioblastoma (Glioblastoma Multiforme) 03/2001 - 08/2000
3	Asthma (Bronchial Asthma) 10/2000 - 05/2000
2	Liver Diseases (Liver Disease) 10/2001 - 08/2000
2	Respiratory Hypersensitivity 10/2000 - 05/2000
2	Eosinophilia 10/2000 - 05/2000
1	Postoperative Pain 07/2006
1	Stress Urinary Incontinence 07/2006
1	Glaucoma 01/2003
1	Cicatrix (Scar) 01/2003
1	Breast Neoplasms (Breast Cancer) 07/2001
1	Glioma (Gliomas) 03/2001
1	Brain Neoplasms (Brain Tumor) 09/2000
1	Inflammation (Inflammations) 08/2000
1	Hepatitis 08/2000
1	Massive Hepatic Necrosis 08/2000
1	Peritonitis 05/2000
1	Carcinoma (Carcinomatosis) 01/2000

Drug/Important Bio-Agent (IBA)

7	Antisense OligonucleotidesIBA 01/2003 - 05/2000
3	OligonucleotidesIBA 10/2001 - 05/2000
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 07/2001 - 09/2000
2	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 03/2001 - 09/2000
2	Phosphatidylinositols (Phosphatidylinositol)IBA 03/2001 - 09/2000
2	Interleukin-5 (Interleukin 5)IBA 10/2000 - 05/2000
2	Proteins (Proteins, Gene)FDA Link 08/2000 - 05/2000
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2003
1	Phosphorothioate OligonucleotidesIBA 01/2003
1	Estradiol (Delestrogen)FDA LinkGeneric 07/2001
1	tissue-factor-pathway inhibitor 2 (PP5)IBA 07/2001
1	Estrogens (Estrogen)FDA Link 07/2001
1	GlucocorticoidsIBA 07/2001
1	Estrogen ReceptorsIBA 07/2001
1	Estrogen Receptor Modulators (Antiestrogen)IBA 07/2001
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 11/2000
1	LigandsIBA 10/2000
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 09/2000
1	Phosphotransferases (Kinase)IBA 09/2000
1	phosphatidylinositol 3,4,5-triphosphateIBA 09/2000
1	LipidsIBA 09/2000
1	phosphatidylinositol 3,4-diphosphateIBA 09/2000
1	Phospholipids (Phosphatides)FDA LinkGeneric 09/2000
1	JNK Mitogen-Activated Protein KinasesIBA 08/2000
1	Interleukin-5 Receptors (Interleukin 5 Receptor)IBA 08/2000
1	Cytokine Receptors (Cytokine Receptor)IBA 08/2000
1	Therapeutic UsesIBA 08/2000
1	Acetaminophen (Paracetamol)FDA LinkGeneric 08/2000
1	Concanavalin AIBA 08/2000
1	ISIS 22023IBA 08/2000
1	RNA (Ribonucleic Acid)IBA 08/2000
1	AllergensIBA 05/2000
1	AntigensIBA 05/2000
1	Mitogen-Activated Protein Kinase 9IBA 03/2000
1	Threonine (L-Threonine)FDA Link 01/2000
1	Serine (L-Serine)FDA Link 01/2000
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2000

Therapy/Procedure

2	Therapeutics 01/2003 - 07/2001
1	Length of Stay 07/2006
1	Operative Surgical Procedures 01/2003
1	Intravenous Administration 05/2000